Intratumor Heterogeneity of HLA-G Expression in Cancer Lesions

Intratumor Heterogeneity of HLA-G Expression in Cancer Lesions

Signaling pathway between human leukocyte antigen (HLA)-G and immune inhibitory receptors immunoglobulin-like transcript (ILT)-2/4 has been acknowledged as one of immune checkpoints, and as a potential target for cancer immunotherapy. Like other immune checkpoints, inter- and even intratumor heterog...

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Bibliographic Details
Main Authors: Xia Zhang, Aifen Lin, Qiu-Yue Han, Jian-Gang Zhang, Qiong-Yuan Chen, Yao-Han Ye, Wen-Jun Zhou, Hui-Hui Xu, Jun Gan, Wei-Hua Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
HLA-G
tumor
heterogeneity
isoform
antibody
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.565759/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.565759/full

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