Intratumor Heterogeneity of HLA-G Expression in Cancer Lesions
Signaling pathway between human leukocyte antigen (HLA)-G and immune inhibitory receptors immunoglobulin-like transcript (ILT)-2/4 has been acknowledged as one of immune checkpoints, and as a potential target for cancer immunotherapy. Like other immune checkpoints, inter- and even intratumor heterog...
Main Authors: | Xia Zhang, Aifen Lin, Qiu-Yue Han, Jian-Gang Zhang, Qiong-Yuan Chen, Yao-Han Ye, Wen-Jun Zhou, Hui-Hui Xu, Jun Gan, Wei-Hua Yan |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.565759/full |
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