The effect of chlorination of nucleotide bases on the conformational properties of thymidine monophosphate

Recent studies on Escherichia coli bacteria cultivation, in which DNA thymine was replaced with 5-chlorouracil have refreshed the problem of understanding the changes to physical properties of DNA monomers resultant from chemical modifications. These studies have shown that the replacement did not a...

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Bibliographic Details
Main Authors: T. M. Mukhina, T. Yu. Nikolaienko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2015-04-01
Series:The Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/05/Mukhina_2_15.pdf