Molecular mechanisms of amyloid-β peptide fibril and oligomer formation: NMR-based challenges
To completely treat and ultimately prevent dementia, it is essential to elucidate its pathogenic mechanisms in detail. There are two major hypotheses for the pathogenesis of Alzheimer’s dementia: the β-amyloid (Aβ) hypothesis and the tau hypothesis. The modified amyloid hypothesis, which proposes th...
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| Format: | Article |
| Language: | English |
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The Biophysical Society of Japan
2023-03-01
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| Series: | Biophysics and Physicobiology |
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| Online Access: | https://doi.org/10.2142/biophysico.bppb-v20.0007 |