7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model.

Accumulation of 7-Ketocholesterol (7KCh) in lipid deposits has been implicated in a variety of chronic diseases including atherosclerosis, Alzheimer's disease and age-related macular degeneration. 7KCh is known to be pro-inflammatory and cytotoxic to various types of cultured cells but little i...

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Bibliographic Details
Main Authors: Juan Amaral, Jung Wha Lee, Joshua Chou, Maria M Campos, Ignacio R Rodríguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3568027?pdf=render