Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats

Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats

Persistent pain affecting patients with inflammatory bowel diseases (IBDs) is still very difficult to treat. Carbonic anhydrase (CA) represents an intriguing pharmacological target considering the anti-hyperalgesic efficacy displayed by CA inhibitors in both inflammatory and neuropathic pain models....

Full description

Bibliographic Details
Main Authors: Elena Lucarini, Alessio Nocentini, Alessandro Bonardi, Niccolò Chiaramonte, Carmen Parisio, Laura Micheli, Alessandra Toti, Valentina Ferrara, Donatello Carrino, Alessandra Pacini, Maria Novella Romanelli, Claudiu T. Supuran, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
IBDs
visceral hypersensitivity
carbonic anhydrase IV
colon
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/10/2540

Internet

https://www.mdpi.com/2073-4409/10/10/2540

Similar Items