Ultra-Short Cyclized β-Boomerang Peptides: Structures, Interactions with Lipopolysaccharide, Antibiotic Potentiator and Wound Healing

Ultra-Short Cyclized β-Boomerang Peptides: Structures, Interactions with Lipopolysaccharide, Antibiotic Potentiator and Wound Healing

Many antibiotics are ineffective in killing Gram-negative bacteria due to the permeability barrier of the outer-membrane LPS. Infections caused by multi-drug-resistant Gram-negative pathogens require new antibiotics, which are often difficult to develop. Antibiotic potentiators disrupt outer-membran...

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Bibliographic Details
Main Authors: Sheetal Sinha, Vidhya Bharathi Dhanabal, Veronica Lavanya Manivannen, Floriana Cappiello, Suet-Mien Tan, Surajit Bhattacharjya
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
antibiotic potentiator
MDR Gram-negative bacteria
cyclic peptide
lipopolysaccharide (LPS)
Online Access:https://www.mdpi.com/1422-0067/24/1/263

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https://www.mdpi.com/1422-0067/24/1/263

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