Structure and phospholipid transfer activity of human PLTP: analysis by molecular modeling and site-directed mutagenesis

The plasma phospholipid transfer protein (PLTP) is an important regulator of high density lipoprotein (HDL) metabolism. We have here, based on sequence alignments of the plasma LPS-binding/lipid transfer protein family and the X-ray structure of the bactericidal/permeability increasing protein (BPI)...

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Bibliographic Details
Main Authors: Jarkko Huuskonen, Gerd Wohlfahrt, Matti Jauhiainen, Christian Ehnholm, Olle Teleman, Vesa M. Olkkonen
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335161