Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by β-arrestins.

Cardiac fibroblasts (CF) play a critical role in post-infarction remodeling which can ultimately lead to pathological fibrosis and heart failure. Recent evidence demonstrates that remote (non-infarct) territory fibrosis is a major mechanism for ventricular dysfunction and arrhythmogenesis. β-arresti...

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Bibliographic Details
Main Authors: Jennifer L Philip, Xianyao Xu, Mei Han, Shahab A Akhter, Md Abdur Razzaque
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219011