Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma

Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma

Histiocytic sarcomas refer to highly aggressive tumors with a poor prognosis that respond poorly to conventional treatment approaches. Oncolytic viruses, which have gained significant traction as a cancer therapy in recent decades, represent a promising option for treating histiocytic sarcomas throu...

Full description

Bibliographic Details
Main Authors: Federico Armando, Adnan Fayyad, Stefanie Arms, Yvonne Barthel, Dirk Schaudien, Karl Rohn, Matteo Gambini, Mara Sophie Lombardo, Andreas Beineke, Wolfgang Baumgärtner, Christina Puff
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
canine distemper virus
canine histiocytic sarcoma
microvessel density
murine xenograft model
oncolytic virus
tumor microenvironment
Online Access:https://www.mdpi.com/1422-0067/22/7/3578

Internet

https://www.mdpi.com/1422-0067/22/7/3578

Similar Items