Transgenic Nicotiana tabacum seeds expressing the Mycobacterium tuberculosis Alanine- and Proline-rich antigen

Abstract The glycoprotein APA (Alanine- and Proline-rich Antigen, a 45/47 kDa antigen complex, Rv1860) is considered as a major immunodominant antigen secreted by M. tuberculosis. This antigen has proved to be highly immunogenic in experimental models and humans, presenting a significant potential f...

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Bibliographic Details
Main Authors: Diego G. Módolo, Cynthia S. Horn, José S. M. Soares, José A. Yunes, Leila M. Lima, Sylvia M. de Sousa, Marcelo Menossi
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:AMB Express
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13568-018-0708-y