Hydrogen Peroxide Is an Endothelium-Derived Hyperpolarizing Factor in Animals and Humans

Vascular endothelium plays an important role in maintaining vascular homeostasis by synthesizing and releasing several vasodilating factors, such as prostacyclin, nitric oxide (NO), and a yet unidentified endothelium-derived hyperpolarizing factor (EDHF). Possible candidates for EDHF include epoxyei...

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Bibliographic Details
Main Authors: Matoba Tetsuya, Hiroaki Shimokawa
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131932688X