Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient i ncreases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an exp erimental probe of adrenal cortisol secretion. Objective:...

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Bibliographic Details
Main Authors: Ferdinand Roelfsema, Peter Y Liu, Rebecca Yang, Paul Takahashi, Johannes D Veldhuis
Format: Article
Language:English
Published: Bioscientifica 2020-07-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/9/7/EC-20-0211.xml