The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice
Abstract Ceruloplasmin (CP) plays an important role in maintaining iron homeostasis. Cp gene knockout (Cp -/- ) mice develop a neurodegenerative disease with aging and show iron accumulation in the brain. However, iron deficiency has also been observed in 3 M Cp -/- mice. The use of systemic Cp gene...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-11-01
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| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-022-05459-4 |