Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration

Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration

Abstract Introduction We tested how tube types (ethylenediaminetetraacetic acid [EDTA], serum, lithium heparin [LiHep], and citrate) and freeze–thaw cycles affect levels of blood biomarkers for Alzheimer's disease (AD) pathophysiology, glial activation, and neuronal injury. Methods Amyloid beta...

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Bibliographic Details
Main Authors: Nicholas J. Ashton, Marc Suárez‐Calvet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Anniina Snellman, Mathias Sauer, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
amyloid beta
biomarkers
blood
citrate
ethylenediaminetetraacetic acid
glial fibrillary acidic protein
Online Access:https://doi.org/10.1002/dad2.12168

Internet

https://doi.org/10.1002/dad2.12168

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