A Calcium Guard in the Outer Membrane: Is VDAC a Regulated Gatekeeper of Mitochondrial Calcium Uptake?

Already in the early 1960s, researchers noted the potential of mitochondria to take up large amounts of Ca<sup>2+</sup>. However, the physiological role and the molecular identity of the mitochondrial Ca<sup>2+</sup> uptake mechanisms remained elusive for a long time. The ide...

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Bibliographic Details
Main Authors: Paulina Sander, Thomas Gudermann, Johann Schredelseker
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/2/946