Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids
Synergistic-aggregation and cross-seeding by two different proteins/peptides in the amyloid aggregation are well evident in various neurological disorders including Alzheimer’s disease. Here, we show co-storage of human Prolactin (PRL), which is associated with lactation in mammals, and neuropeptide...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/73835 |