Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.

Alcohol dependence and associated cognitive impairments apparently result from neuroadaptations to chronic alcohol consumption involving changes in expression of multiple genes. Here we investigated whether transcription factors of Nuclear Factor-kappaB (NF-kappaB) family, controlling neuronal plast...

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Bibliographic Details
Main Authors: Anna Okvist, Sofia Johansson, Alexander Kuzmin, Igor Bazov, Roxana Merino-Martinez, Igor Ponomarev, R Dayne Mayfield, R Adron Harris, Donna Sheedy, Therese Garrick, Clive Harper, Yasmin L Hurd, Lars Terenius, Tomas J Ekström, Georgy Bakalkin, Tatjana Yakovleva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1976556?pdf=render