Activation of AHR by ITE improves cardiac remodelling and function in rats after myocardial infarction

Activation of AHR by ITE improves cardiac remodelling and function in rats after myocardial infarction

Abstract Aims Left ventricular remodelling subsequent to myocardial infarction (MI) constitutes a pivotal underlying cause of heart failure. Intervention with the nontoxic endogenous aryl hydrocarbon receptor (AHR) agonist 2‐(1′H‐indole‐3′‐carbonyl)‐thiazole‐4‐carboxylic acid methyl ester (ITE) in t...

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Bibliographic Details
Main Authors: Xiaoyan Lin, Weiqiang Liu, Yong Chu, Hailin Zhang, Lishan Zeng, Yifei Lin, Kai Kang, Feng Peng, Jinxiu Lin, Chunkai Huang, Dajun Chai
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:ESC Heart Failure
Subjects:
AHR agonist
Myocardial infarction
Ventricular remodelling
Apoptosis
Akt/p70S6K
Online Access:https://doi.org/10.1002/ehf2.14532

Internet

https://doi.org/10.1002/ehf2.14532

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