Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte globulin

Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte globulin

Abstract Cyclosporine-A (CsA) is used to prevent acute graft-versus-host disease (aGvHD). European Society for Blood and Marrow transplantation (EBMT) recommends a CsA target serum concentration of 200–300 µg/L during the first month after allogeneic hematopoietic stem cell transplantation (HSCT). W...

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Bibliographic Details
Main Authors: Mikael Lisak, Malin Nicklasson, Robert Palmason, Stina Wichert, Cecila Isaksson, Per-Ola Andersson, Jan-Erik Johansson, Stig Lenhoff, Mats Brune, Markus Hansson
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50105-4

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https://doi.org/10.1038/s41598-023-50105-4

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