Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease

Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease

Heart tissue inflammation, progressive fibrosis and electrocardiographic alterations occur in approximately 30% of patients infected by Trypanosoma cruzi, 10-30 years after infection. Further, plasma levels of tumour necrosis factor (TNF) and nitric oxide (NO) are associated with the degree of heart...

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Bibliographic Details
Main Authors: Isabela Resende Pereira, Glaucia Vilar-Pereira, Andrea Alice da Silva, Joseli Lannes-Vieira
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2014-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Chagas disease
cardiomyopathy
experimental model
tumour necrosis factor
nitric oxide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300289&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300289&lng=en&tlng=en

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