Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
Heart tissue inflammation, progressive fibrosis and electrocardiographic alterations occur in approximately 30% of patients infected by Trypanosoma cruzi, 10-30 years after infection. Further, plasma levels of tumour necrosis factor (TNF) and nitric oxide (NO) are associated with the degree of heart...
Main Authors: | Isabela Resende Pereira, Glaucia Vilar-Pereira, Andrea Alice da Silva, Joseli Lannes-Vieira |
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Format: | Article |
Language: | English |
Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2014-06-01
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Series: | Memorias do Instituto Oswaldo Cruz |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300289&lng=en&tlng=en |
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