Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

The anti-inflammatory role of regulatory B cells (Breg cells) has been associated with IL-35 based on studies of experimental autoimmune uveitis and encephalitis. The role of Breg cells and IL-35<sup>+</sup> Breg cells for type 1 diabetes (T1D) remains to be investigated. We studied PBMC...

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Bibliographic Details
Main Authors: Zhengkang Luo, Sara Lundin, Mariela Mejia-Cordova, Imane Hassani, Martin Blixt, Daisy Hjelmqvist, Joey Lau, Daniel Espes, Per-Ola Carlsson, Stellan Sandler, Kailash Singh
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
breg cells
IL-35
type 1 diabetes
Online Access:https://www.mdpi.com/1422-0067/22/23/12988

Internet

https://www.mdpi.com/1422-0067/22/23/12988

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