The use of synaptic biomarkers in cerebrospinal fluid to differentiate behavioral variant of frontotemporal dementia from primary psychiatric disorders and Alzheimer’s disease

The use of synaptic biomarkers in cerebrospinal fluid to differentiate behavioral variant of frontotemporal dementia from primary psychiatric disorders and Alzheimer’s disease

Abstract Background Lack of early molecular biomarkers in sporadic behavioral variants of frontotemporal dementia (bvFTD) and its clinical overlap with primary psychiatric disorders (PPD) hampers its diagnostic distinction. Synaptic dysfunction is an early feature in bvFTD and identification of spec...

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Bibliographic Details
Main Authors: Shreyasee Das, Marie-Paule E. van Engelen, Julie Goossens, Dirk Jacobs, Bram Bongers, Jay L. P. Fieldhouse, Yolande A. L. Pijnenburg, Charlotte E. Teunissen, Eugeen Vanmechelen, Inge M. W. Verberk
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Synaptic biomarkers
Frontotemporal dementia
Primary psychiatric disorders
Differential diagnosis
Online Access:https://doi.org/10.1186/s13195-024-01409-8

Internet

https://doi.org/10.1186/s13195-024-01409-8

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