Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B.

Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B.

CD8(+) T cells are essential for host defense to intracellular bacterial pathogens such as Mycobacterium tuberculosis (Mtb), Salmonella species, and Listeria monocytogenes, yet the repertoire and dominance pattern of human CD8 antigens for these pathogens remains poorly characterized. Tuberculosis (...

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Bibliographic Details
Main Authors: Deborah A Lewinsohn, Ervina Winata, Gwendolyn M Swarbrick, Katie E Tanner, Matthew S Cook, Megan D Null, Meghan E Cansler, Alessandro Sette, John Sidney, David M Lewinsohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2323292?pdf=render

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http://europepmc.org/articles/PMC2323292?pdf=render

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