Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs

Abstract One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes. The functional requirement and regulatory landscape for the majority of A-to-I editing events are, at present, unc...

Full description

Bibliographic Details
Main Authors: Carl R. Walkley, Jin Billy Li
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1347-3