Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
Abstract One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes. The functional requirement and regulatory landscape for the majority of A-to-I editing events are, at present, unc...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-017-1347-3 |