Pamidronate for the treatment of osteoporosis secondary to chronic cholestatic liver disease in Wistar rats

Pamidronate for the treatment of osteoporosis secondary to chronic cholestatic liver disease in Wistar rats

Osteoporosis is a major complication of chronic cholestatic liver disease (CCLD). We evaluated the efficacy of using disodium pamidronate (1.0 mg/kg body weight) for the prevention (Pr) or treatment (Tr) of cholestasis-induced osteoporosis in male Wistar rats: sham-operated (Sham = 12); bile duct-li...

Full description

Bibliographic Details
Main Authors: F.A. Pereira, R. Mattar, I. Facincani, H.L.A. Defino, L.N.Z. Ramalho, V. Jorgetti, J.B. Volpon, F.J.A. de Paula
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Hepatic osteodystrophy
Osteoporosis pathogenesis
Growth factors
Biomechanics
Animal models
Pamidronate
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200021&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200021&lng=en&tlng=en

Similar Items