Synthesis and Antiplasmodial Activity of Novel Bioinspired Imidazolidinedione Derivatives

Synthesis and Antiplasmodial Activity of Novel Bioinspired Imidazolidinedione Derivatives

Malaria is an enormous threat to public health, due to the emergence of <i>Plasmodium falciparum</i> resistance to widely-used antimalarials, such as chloroquine (CQ). Current antimalarial drugs are aromatic heterocyclic derivatives, most often containing a basic component with an added...

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Bibliographic Details
Main Authors: Anna Jaromin, Anna Czopek, Silvia Parapini, Nicoletta Basilico, Ernest Misiak, Jerzy Gubernator, Agnieszka Zagórska
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomolecules
Subjects:
Imidazolidine-2,4-dione derivatives
<i>Plasmodium falciparum</i>
antiparasitic agents
antimalarial
drug resistance
cytotoxicity
Online Access:https://www.mdpi.com/2218-273X/11/1/33

Internet

https://www.mdpi.com/2218-273X/11/1/33

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