Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light

As one of the ubiquitous second messengers, the intracellular Ca2+, has been revealed to be a pivotal regulator of various cellular functions. Two major sources are involved in the initiation of Ca2+-dependent signals: influx from the extracellular space and release from the intracellular Ca2+ store...

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Bibliographic Details
Main Authors: Toshifumi Asano, Hiroyuki Igarashi, Toru Ishizuka, Hiromu Yawo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00561/full