Tumor-specific interendothelial adhesion mediated by FLRT2 facilitates cancer aggressiveness

Tumor-specific interendothelial adhesion mediated by FLRT2 facilitates cancer aggressiveness

Blood vessel abnormalization alters cancer cell metabolism and promotes cancer dissemination and metastasis. However, the biological features of the abnormalized blood vessels that facilitate cancer progression and whether they can be targeted therapeutically have not been fully investigated. Here,...

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Bibliographic Details
Main Authors: Tomofumi Ando, Ikue Tai-Nagara, Yuki Sugiura, Dai Kusumoto, Koji Okabayashi, Yasuaki Kido, Kohji Sato, Hideyuki Saya, Sutip Navankasattusas, Dean Y. Li, Makoto Suematsu, Yuko Kitagawa, Elena Seiradake, Satoru Yamagishi, Yoshiaki Kubota
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-03-01
Series:The Journal of Clinical Investigation
Subjects:
Angiogenesis
Vascular biology
Online Access:https://doi.org/10.1172/JCI153626

Internet

https://doi.org/10.1172/JCI153626

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