Study of CDH1 germline mutation in hereditary diffuse gastric cancer and lobular breast cancer: a multicenter study in Iran

Study of CDH1 germline mutation in hereditary diffuse gastric cancer and lobular breast cancer: a multicenter study in Iran

Introduction: Mutations occurring in the CDH1 gene elevate the susceptibility to the development of hereditary diffuse gastric cancer (HDGC) as well as lobular breast cancer (LBC). LBCs with CDH1 germline mutations are classified as hereditary breast cancers, devoid of any indication of gastric car...

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Bibliographic Details
Main Authors: Marveh Rahmati, Elmira Ebrahimi, Reza Shirkoohi, Habibollah Mahmoodzadeh, Ahad Mohammanjad, Hedyeh Malekisarvar, Zahra Valizadeh, Marzieh Dehghani, Shirin Haghighat, Maryam Marzban, Kazem Zendehdel
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-03-01
Series:Basic & Clinical Cancer Research
Subjects:
CDH1 mutation
Hereditary Diffuse Gastric Cancer
Lobular breast cancer
Prophylactic gastrectomy
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/497

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https://bccr.tums.ac.ir/index.php/bccrj/article/view/497

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