Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity

Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity

Summary: The gut microbiome has emerged as a key regulator of obesity; however, its role in brown adipose tissue (BAT) metabolism and association with obesity remain to be elucidated. We found that the levels of circulating branched-chain amino acids (BCAA) and their cognate α-ketoacids (BCKA) were...

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Bibliographic Details
Main Authors: Naofumi Yoshida, Tomoya Yamashita, Tatsunori Osone, Tetsuya Hosooka, Masakazu Shinohara, Seiichi Kitahama, Kengo Sasaki, Daisuke Sasaki, Takeshi Yoneshiro, Tomohiro Suzuki, Takuo Emoto, Yoshihiro Saito, Genki Ozawa, Yushi Hirota, Yasuyuki Kitaura, Yoshiharu Shimomura, Yuko Okamatsu-Ogura, Masayuki Saito, Akihiko Kondo, Shingo Kajimura, Takeshi Inagaki, Wataru Ogawa, Takuji Yamada, Ken-ichi Hirata
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Computer systems organization
Energy engineering
Energy systems
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221013110

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http://www.sciencedirect.com/science/article/pii/S2589004221013110

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