Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis

Exchange proteins directly activated by cAMP (EPAC1 and EPAC2) are one of the several families of cellular effectors of the prototypical second messenger cAMP. To understand the origin and molecular evolution of EPAC proteins, we performed a comprehensive phylogenetic analysis of EPAC1 and EPAC2. Ou...

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Bibliographic Details
Main Authors: Zhuofu Ni, Xiaodong Cheng
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/10/2750