The efficacy and safety of a nicotine conjugate vaccine (NicVAX<sup>®</sup>) or placebo co-administered with varenicline (Champix<sup>®</sup>) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

The efficacy and safety of a nicotine conjugate vaccine (NicVAX<sup>®</sup>) or placebo co-administered with varenicline (Champix<sup>®</sup>) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

<p>Abstract</p> <p>Background</p> <p>A potential new treatment in smoking cessation and relapse prevention is nicotine vaccination which is based on active immunization against the nicotine molecule. This immunization will elicit the immune system to produce nicotine-sp...

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Bibliographic Details
Main Authors: Hoogsteder Philippe HJ, Kotz Daniel, van Spiegel Paul I, Viechtbauer Wolfgang, Brauer Ruth, Kessler Paul D, Kalnik Matthew W, Fahim Raafat EF, van Schayck Onno CP
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Public Health
Subjects:
Nicotine vaccination
NicVAX
Varenicline
Combination therapy
Efficacy
Safety
Immunogenicity
Randomized controlled trial
Online Access:http://www.biomedcentral.com/1471-2458/12/1052

Internet

http://www.biomedcentral.com/1471-2458/12/1052

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