First-In-Human Results on the Biodistribution, Pharmacokinetics, and Dosimetry of [<sup>177</sup>Lu]Lu-DOTA.SA.FAPi and [<sup>177</sup>Lu]Lu-DOTAGA.(SA.FAPi)<sub>2</sub>

First-In-Human Results on the Biodistribution, Pharmacokinetics, and Dosimetry of [<sup>177</sup>Lu]Lu-DOTA.SA.FAPi and [<sup>177</sup>Lu]Lu-DOTAGA.(SA.FAPi)<sub>2</sub>

Recently, great interest has been gained regarding fibroblast activation protein (FAP) as an excellent target for theranostics. Several FAP inhibitor molecules such as [<sup>68</sup>Ga]Ga-labelled FAPI-02, 04, 46, and DOTA.SA.FAPi have been introduced and are highly promising molecular t...

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Bibliographic Details
Main Authors: Sanjana Ballal, Madhav Prasad Yadav, Euy Sung Moon, Vasko S Kramer, Frank Roesch, Samta Kumari, Chandrasekhar Bal
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceuticals
Subjects:
[<sup>68</sup>Ga]Ga-DOTA.SA.FAPi PET/CT
[<sup>177</sup>Lu]Lu-DOTA.SA.FAPi
[<sup>177</sup>Lu]Lu-DOTAGA.(SA.FAPi)<sub>2</sub>
biodistribution
dosimetry
pharmacokinetics
Online Access:https://www.mdpi.com/1424-8247/14/12/1212

Internet

https://www.mdpi.com/1424-8247/14/12/1212

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