In silico identification of chemical compounds in Spondias mombin targeting aldose reductase and glycogen synthase kinase 3β to abate diabetes mellitus

In silico identification of chemical compounds in Spondias mombin targeting aldose reductase and glycogen synthase kinase 3β to abate diabetes mellitus

Aldose reductase and glycogen synthase kinase 3β (GSK3β) represent two of the ideal drug targets in diabetes due to their role in the pathogenesis of diabetes. Studies have shown that plant compounds provide therapeutics in diabetes management. This study identified some compounds in S. mombin as du...

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Bibliographic Details
Main Authors: B.O. Ajiboye, T.M. Fagbola, I.M. Folorunso, A.W. Salami, O.N. Aletile, B.A. Akomolede, F.I. Ayemoni, K.I. Akinfemiwa, V.O. Anwo, M.I. Ojeleke, B.E. Oyinloye
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Diabetes
Aldose reductase
Glycogen synthase 3β
Molecular docking
Drug candidate
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822002635

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http://www.sciencedirect.com/science/article/pii/S2352914822002635

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