Romosozumab for the treatment of osteoporosis

Romosozumab, a specific inhibitor of sclerostin, is a unique approach to therapy for postmenopausal osteoporosis and related disorders. The elucidation of sclerostin deficiency as the molecular defect of syndromes of high bone mass with normal quality, and the pivotal role of sclerostin as a mediato...

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Bibliographic Details
Main Author: Michael R. McClung
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Osteoporosis and Sarcopenia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405525518300062