Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology: A Randomized Controlled Trial Comparing Push Injections with One-Hour Infusions (The VINCA Trial)

Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology: A Randomized Controlled Trial Comparing Push Injections with One-Hour Infusions (The VINCA Trial)

Vincristine (VCR) is a frequently used chemotherapeutic agent. However, it can lead to VCR-induced peripheral neuropathy (VIPN). In this study we investigated if one-hour infusions of VCR instead of push-injections reduces VIPN in pediatric oncology patients. We conducted a multicenter randomized co...

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Bibliographic Details
Main Authors: Mirjam Esther van de Velde, Gertjan J. L. Kaspers, Floor C. H. Abbink, Jos W. R. Twisk, Inge M. van der Sluis, Cor van den Bos, Marry M. van den Heuvel-Eibrink, Heidi Segers, Christophe Chantrain, Jutte van der Werff ten Bosch, Leen Willems, Marleen H. van den Berg
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
neurotoxicity
exposure
children
cancer
vincristine
toxicity
Online Access:https://www.mdpi.com/2072-6694/12/12/3745

Internet

https://www.mdpi.com/2072-6694/12/12/3745

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