The Novel Compounds That Activate Farnesoid X Receptor: the Diversity of Their Effects on Gene Expression

The Novel Compounds That Activate Farnesoid X Receptor: the Diversity of Their Effects on Gene Expression

Farnesoid X receptor (FXR) controls the expression of critical genes in bile acid and cholesterol homeostasis. To study FXR and to develop a regulator of cholesterol, some nonsteroidal and steroidal ligands have been found in addition to endogenous ligands for FXR. In this study, we discovered five...

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Bibliographic Details
Main Authors: Takuo Suzuki, Norimasa Tamehiro, Yoji Sato, Tetsu Kobayashi, Akiko Ishii-Watabe, Youichi Shinozaki, Tomoko Nishimaki-Mogami, Toshihiro Hashimoto, Yoshinori Asakawa, Kazuhide Inoue, Yasuo Ohno, Teruhide Yamaguchi, Toru Kawanishi
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131931415X

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http://www.sciencedirect.com/science/article/pii/S134786131931415X

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