Biological potency evaluation and characterization of rhG-CSF in pharmaceutical products Avaliação biológica da potência e caracterização de rhG-CSF em produtos farmacêuticos

The identification of rhG-CSF was carried out in pharmaceutical preparations by non-reducing polyacrylamide gel electrophoresis and western blotting with specific antibodies, showing a single band in the 19 kDa region. The potency was assessed by the neutropenia mouse bioassay giving values between...

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Bibliographic Details
Main Authors: Cristiane F. Codevilla, Thiago Barth, Liberato Brum Júnior, Marcio Fronza, Sérgio L. Dalmora
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842004000200007