Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury
Abstract Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of motor circuits during which supraspinal connections form new contacts onto spinal relay neurons. We have recently identified a critical role of the presynaptic organizer FGF22 for the formation of n...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2023-02-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.202216111 |