Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury

Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury

Abstract Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of motor circuits during which supraspinal connections form new contacts onto spinal relay neurons. We have recently identified a critical role of the presynaptic organizer FGF22 for the formation of n...

Повний опис

Бібліографічні деталі
Автори: Almir Aljović, Anne Jacobi, Maite Marcantoni, Fritz Kagerer, Kristina Loy, Arek Kendirli, Jonas Bräutigam, Luca Fabbio, Valérie Van Steenbergen, Katarzyna Pleśniar, Martin Kerschensteiner, Florence M Bareyre
Формат: Стаття
Мова:English
Опубліковано: Springer Nature 2023-01-01
Серія:EMBO Molecular Medicine
Предмети:
adeno‐associated virus
FGF22
gene therapy
recovery
spinal cord injury
Онлайн доступ:https://doi.org/10.15252/emmm.202216111

Інтернет

https://doi.org/10.15252/emmm.202216111

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