A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice

A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice

Human metapneumovirus (HMPV) and human respiratory virus (HRSV) are two leading causes of acute respiratory tract infection in young children. While there is no licensed drug against HMPV, the monoclonal antibody (mAb) Palivizumab is approved against HRSV for prophylaxis use only. Novel therapeutics...

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Bibliographic Details
Main Authors: Hugues Fausther-Bovendo, Marie-Eve Hamelin, Julie Carbonneau, Marie-Christine Venable, Liva Checkmahomed, Pierre-Olivier Lavoie, Marie-Ève Ouellet, Guy Boivin, Marc-André D’Aoust, Gary P. Kobinger
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
HMPV
HRSV
therapeutic antibodies
Online Access:https://www.mdpi.com/2227-9059/10/10/2516

Internet

https://www.mdpi.com/2227-9059/10/10/2516

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