Levels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression

Levels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression

Abstract Dysregulation of the alternative pathway (AP) of the complement system is a significant contributor to age-related macular degeneration (AMD), a primary cause of irreversible vision loss worldwide. Here, we assess the contribution of the liver-produced complement factor H-related 4 protein...

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Bibliographic Details
Main Authors: M. A. Zouache, B. T. Richards, C. M. Pappas, R. A. Anstadt, J. Liu, T. Corsetti, S. Matthews, N. A. Seager, S. Schmitz-Valckenberg, M. Fleckenstein, W. C. Hubbard, J. Thomas, J. L. Hageman, B. L. Williams, G. S. Hageman
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44605-0

Internet

https://doi.org/10.1038/s41467-023-44605-0

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