Hepatocyte Ploidy Is a Diversity Factor for Liver Homeostasis

Polyploidy, the existence of cells containing more than one pair of chromosomes, is a well-known feature of mammalian hepatocytes. Polyploid hepatocytes are found either as cells with a single polyploid nucleus or as multinucleated cells with diploid or even polyploid nuclei. In this study, we evalu...

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Bibliographic Details
Main Authors: Clemens Kreutz, Sabine MacNelly, Marie Follo, Astrid Wäldin, Petra Binninger-Lacour, Jens Timmer, María M. Bartolomé-Rodríguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00862/full