Demystifying Excess Immune Response in COVID-19 to Reposition an Orphan Drug for Down-Regulation of NF-κB: A Systematic Review

Demystifying Excess Immune Response in COVID-19 to Reposition an Orphan Drug for Down-Regulation of NF-κB: A Systematic Review

The immunological findings from autopsies, biopsies, and various studies in COVID-19 patients show that the major cause of morbidity and mortality in COVID-19 is excess immune response resulting in hyper-inflammation. With the objective to review various mechanisms of excess immune response in adult...

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Bibliographic Details
Main Authors: Apparao Peddapalli, Manish Gehani, Arunasree M. Kalle, Siva R. Peddapalli, Angela E. Peter, Shashwat Sharad
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
COVID-19
cytokine storm
SARS-CoV-2
repositioning
histamine-conjugated-normal human immunoglobulin
excess immune response
Online Access:https://www.mdpi.com/1999-4915/13/3/378

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https://www.mdpi.com/1999-4915/13/3/378

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