Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients With Ulcerative Colitis

Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients With Ulcerative Colitis

As a major component of the enteroendocrine system, enterochromaffin (EC) cells play a key role in ulcerative colitis (UC). However, the scarcity of EC cells has limited the investigation of their function. In this study, we applied digital spatial profiling to acquire transcriptomic data for EC cel...

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Bibliographic Details
Main Authors: Dongping Lyu, Guanjun Kou, Shiyang Li, Lixiang Li, Bing Li, Ruchen Zhou, Xiaoxiao Yang, Wenyu Tian, Yanqing Li, Xiuli Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
enterochromaffin cell
ulcerative colitis
digital spatial profiling
chromogranin B
single-cell RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.841090/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.841090/full

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