Identifying potential risk genes and pathways for neuropsychiatric and substance use disorders using intermediate molecular mediator information

Identifying potential risk genes and pathways for neuropsychiatric and substance use disorders using intermediate molecular mediator information

Neuropsychiatric and substance use disorders (NPSUDs) have a complex etiology that includes environmental and polygenic risk factors with significant cross-trait genetic correlations. Genome-wide association studies (GWAS) of NPSUDs yield numerous association signals. However, for most of these regi...

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Bibliographic Details
Main Authors: Huseyin Gedik, Tan Hoang Nguyen, Roseann E. Peterson, Christos Chatzinakos, Vladimir I. Vladimirov, Brien P. Riley, Silviu-Alin Bacanu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
eQTL
pQTL
mQTL
Mendelian randomization
alcohol use disorder
bipolar disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1191264/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1191264/full

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