Predicting cognitive decline: Which is more useful, baseline amyloid levels or longitudinal change?

Predicting cognitive decline: Which is more useful, baseline amyloid levels or longitudinal change?

The use of biomarkers for the early detection of Alzheimer’s disease (AD) is crucial for developing potential therapeutic treatments. Positron Emission Tomography (PET) is a well-established tool used to detect β-amyloid (Aβ) plaques in the brain. Previous studies have shown that cross-sectional bio...

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Bibliographic Details
Main Authors: Gengsheng Chen, Nicole S. McKay, Brian A. Gordon, Jingxia Liu, Nelly Joseph-Mathurin, Suzanne E. Schindler, Jason Hassenstab, Andrew J. Aschenbrenner, Qing Wang, Stephanie A. Schultz, Yi Su, Pamela J LaMontagne, Sarah J. Keefe, Parinaz Massoumzadeh, Carlos Cruchaga, Chengjie Xiong, John C. Morris, Tammie L.S. Benzinger
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
Amyloid
PET
Cognition
Alzheimer’s disease
Longitudinal study
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223002425

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http://www.sciencedirect.com/science/article/pii/S2213158223002425

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