Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main pro...
मुख्य लेखकों: | Shailima Rampogu, Tae Sung Jung, Min Woo Ha, Keun Woo Lee |
---|---|
स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Nature Portfolio
2023-06-01
|
श्रृंखला: | Scientific Reports |
ऑनलाइन पहुंच: | https://doi.org/10.1038/s41598-023-36342-7 |
समान संसाधन
-
Virtual screening, molecular docking, molecular dynamics simulations and free energy calculations to discover potential DDX3 inhibitors
द्वारा: Shailima Rampogu, और अन्य
प्रकाशित: (2022-07-01) -
Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors
द्वारा: Shailima Rampogu, और अन्य
प्रकाशित: (2023-02-01) -
Computational Approaches to Discover Novel Natural Compounds for SARS‐CoV‐2 Therapeutics
द्वारा: Dr. Shailima Rampogu, और अन्य
प्रकाशित: (2021-05-01) -
Computational repurposing of asthma drugs as potential inhibitors of SARS-CoV-2 Mpro
द्वारा: A. Hussain, और अन्य
प्रकाशित: (2022-04-01) -
Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase
द्वारा: Syed Hani Abidi, और अन्य
प्रकाशित: (2021-05-01)